Triterpenoids from Roots of Glycine max (L.) Merr

Metanolic root extract of Glycine max (L.) Merr. was chromatographed, affording three triterpenoids 1-3. The compound 3 was isolated from microorganism called Fusarium sporotrichioides but never been isolated from any plant sources. Compounds 1-3 showed cytotoxic activity against HT-59 human cancer...

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Published inAgricultural chemistry and biotechnology Vol. 49; no. 2
Main Authors Lee, J.H. (Gyeongsang National University, Jinju, Republic of Korea), Seo, K.I. (Sunchon National University, Sunchon, Republic of Korea), Kang, N.S. (Gyeongsang National University, Jinju, Republic of Korea), Yang, M.S. (Gyeongsang National University, Jinju, Republic of Korea), Park, K.H. (Gyeongsang National University, Jinju, Republic of Korea), E-mail: khpark@gsnu.ac.kr
Format Journal Article
LanguageEnglish
Published 01.06.2006
Subjects
antibacterial
GLYCINE MAX
HT-59 human cancer cell
TOXICIDAD
TOXICITE
TOXICITY
TRITERPENOIDE
TRITERPENOIDOS
TRITERPENOIDS
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Summary:Metanolic root extract of Glycine max (L.) Merr. was chromatographed, affording three triterpenoids 1-3. The compound 3 was isolated from microorganism called Fusarium sporotrichioides but never been isolated from any plant sources. Compounds 1-3 showed cytotoxic activity against HT-59 human cancer cell line with IC∧50 values of 62.9, 20.0, and 44.2 μM, respectively. Compound 3 showed significant activities against Gram-positive bacterial such as Bacillus cereus, Bacillus subtilis, and Staphylococcs aureus.
Bibliography:2007000318
F60
ISSN:1229-2737