Stability of Vitamin-C Inclusion Complexes Prepared using a Solvent Evaporation Method

Vitamin-C is one of the typical bioactive substances widely used in the cosmetic and pharmaceutical applications. It is well known that the bioavailability of vitamin-C decreases with time because it is spontaneously oxidized in the presence of oxygen. In this study, vitamin-C inclusion complexes we...

Full description

Saved in:
Bibliographic Details
Published inKorean Journal of Biotechnology and Bioengineering Vol. 21; no. 2
Main Authors Yang, J.M. (The University of Suwon, Hwaseong, Republic of Korea), Lee, Y.K. (The University of Suwon, Hwaseong, Republic of Korea), Kim, E.M. (The University of Suwon, Hwaseong, Republic of Korea), Jung, I.I. (The University of Suwon, Hwaseong, Republic of Korea), Ryu, J.H. (The University of Suwon, Hwaseong, Republic of Korea), Lim, G.B. (The University of Suwon, Hwaseong, Republic of Korea), E-mail: gblim@suwon.ac.kr
Format Journal Article
LanguageKorean
Published 01.04.2006
Subjects
DEXTRINAS
DEXTRINE
DEXTRINS
ECONOMIC STABILIZATION
ESTABILIZACION ECONOMICA
inclusion comples
solvent evaporation
STABILISATION ECONOMIQUE
Vitamin-C
Online AccessGet full text

Cover

More Information
Summary:Vitamin-C is one of the typical bioactive substances widely used in the cosmetic and pharmaceutical applications. It is well known that the bioavailability of vitamin-C decreases with time because it is spontaneously oxidized in the presence of oxygen. In this study, vitamin-C inclusion complexes were prepared by formulating vitamin-C with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) to protect vitamin-C from being oxidized. Vitamin-C inclusion complexes were prepared by a solvent evaporation method using a rotary evaporator and various solvents of different dielectric constant such as ethanol, methanol and distilled deionized water to investigate the effect of solvent polarity on the stability of vitamin-C.
Bibliography:E21
2006018005
ISSN:1225-7117