Safety Evaluation of Tobacco Substitute (Herbrette); Inhalation Toxicity, Mutagenicity and Immunotoxicity

• Published in: Journal of toxicology and public health Vol. 20; no. 4
• Main Authors: Song, K.S. (Seoul National University, Seoul, Republic of Korea), Yoo, G.Y. (3G CARE, Seoul, Republic of Korea), Park, K.H. (Seoul National University, Seoul, Republic of Korea), Song, S.O. (Seoul National University, Seoul, Republic of Korea), Kim, H.W. (Seoul National University, Seoul, Republic of Korea), Kim, J.S. (Seoul National University, Seoul, Republic of Korea), Park, J.H. (Seoul National University, Seoul, Republic of Korea), Eu, G.J. (Seoul National University, Seoul, Republic of Korea), Hua, J. (Seoul National University, Seoul, Republic of Korea), Cho, H.S. (Seoul National University, Seoul, Republic of Korea), Hwang, S.K. (Seoul National University, Seoul, Republic of Korea), Chang, S.H. (Seoul National University, Seoul, Republic of Korea), Tehrani, Arash Minai (Seoul National University, Seoul, Republic of Korea), Yu, K.N. (Seoul National University, Seoul, Republic of Korea), Chae, C.H. (Seoul National University, Seoul, Republic of Korea), Cho, M.H. (Seoul National University, Seoul, Republic of Korea), E-mail: mchotox@snu.ac.kr
• Format: Journal Article
• Language: English
• Published: 01.12.2004
• Subjects: Herbrette; Immunotoxicity; Inhalation toxicity; MUTAGENICIDAD; MUTAGENICITE; MUTAGENICITY; TABAC; TABACO; TOBACCO; Tobacco substitute; TOXICIDAD; TOXICITE; TOXICITY

Inhalation toxicity, mutagenicity, and immunotoxicity tests were performed using a smoke generation system to investigate the safety of Herbrette, a tobacco substitute made with the leaves of Perilla frutescens. ICR mice were exposed to nicotine-free Herbrette smoke with concentrations of 0 (control...