DPPH Radical Scavenger Activity and Antioxidant Effects of Cham-Dang-Gui (Angelica gigas)

• Published in: Han'guk Sikp'um Yŏngyang Kwahakhoe chi Vol. 33; no. 7
• Main Authors: Kang, S.A.(Konkuk University, Seoul, Republic of Korea), Han, J.A.;Choue, R.W.(Kyung Hee University, Seoul, Republic of Korea)E-mail:rwcho@khu.ac.kr, Jang, K.H.(Samcheok University, Samcheok, Republic of Korea)
• Format: Journal Article
• Language: Korean
• Subjects: Angelica gigas; antioxidant effect; ANTIOXIDANTES; ANTIOXIDANTS; ANTIOXYDANT; Cham-Dang-Gui; DPPH radical scavenger activity; DPPH Radical 소거 활성; MDA; 참당귀; 항산화 효과
• ISSN: 1226-3311

This study was carried out to evaluate the free radical scavenging effect and antioxidant effect of Cham-Dang-Gui (Angelica gigas) on cyclophosphamide (CYP) injected rats. Rats were divided into five groups: CON (normal group), ANS (CYP-injected and normal diet group), AND (CYP-injected and normal diet and Cham-Dang-Gui-treated group), ALS (CYP-injected and low iron diet group), and ALD (CYP-injected and low iron diet and Cham-Dang-Gui-treated group). CYP (30 mg/kg) was intraperitoneally injected to rats for early 3 days. Saline or Cham-Dang-Gui was administrated orally for entire experimental period. DPPH radical scavenger activity was measured by DPPH method, it was shown higher in methanol extract (81.5％) than in water extract (66.3％) of Cham-Dang-Gui.