Inhibition of Growth and Collagenase Activity of the Extract from Salvia miltiorrhiza against Microorganisms Causing Periodontal Diseases

This study was carried out to evaluate the inhibition of growth and collagenase activity of Salvia miltiorrhiza Bunge against microorganisms causing periodontal diseases. The ethanol extract of Salvia miltiorrhiza showed sig-nificant growth inhibition against microorganisms causing periodontal disea...

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Published inThe Korean Journal of Microbiology Vol. 40; no. 2
Main Authors Min, E.G.;Kim, Y.H.(Dongguk University, Gyeongju, Republic of Korea), Kum, S.I.(Shin-Hwa Pharm. Research Inst., Gyeongju, Republic of Korea), Han, Y.H.(Graduate School, Dongguk University, Gyeongju, Republic of Korea)E-mail:yhhan@dongguk.ac.kr
Format Journal Article
LanguageKorean
Subjects
AFFECTION BUCCALE
collagenase
ENFERMEDADES DE LA BOCA
MOUTH DISEASES
periodontal diseases
PROTEASAS
PROTEASE
PROTEASES
Salvia miltiorrhiza
단삼
생육억제
추출물
치주질환유발 세균
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Summary:This study was carried out to evaluate the inhibition of growth and collagenase activity of Salvia miltiorrhiza Bunge against microorganisms causing periodontal diseases. The ethanol extract of Salvia miltiorrhiza showed sig-nificant growth inhibition against microorganisms causing periodontal diseases. Ethanol extract was further fractionated with organic solvents in the order of hexane, chloroform and ethyl acetate. Among the fractions tested, the hexane fraction showed the highest cell growth inhibition.
Bibliography:2005009041
L73
ISSN:0440-2413