Vitamin E as an adjuvant in NDV and IBDV vaccines for poultry

The immunogenicity and protective capability of D, L-±-tocopheryl acetate (vitamin E) adjuvanted Newcastle disease (ND) + Infectious bursal disease (IBD) inactivated vaccine was evaluated in broiler chicks. Results showed that the vaccine supplemented with vitamin E induced more rapid and higher ant...

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Bibliographic Details
Published inIndian journal of veterinary pathology Vol. 35; no. 2
Main Authors Bodade, Jyoti, Kalorey, D.R, Kurkure, N.V, Tongaonkar, S.S
Format Journal Article
LanguageEnglish
Published 01.12.2011
Subjects
ADJUVANT
ADJUVANTS
AVES DE CORRAL
COADYUVANTES
http://www.fao.org/aos/agrovoc#c_15230
http://www.fao.org/aos/agrovoc#c_16381
http://www.fao.org/aos/agrovoc#c_35738
http://www.fao.org/aos/agrovoc#c_3799
http://www.fao.org/aos/agrovoc#c_6145
http://www.fao.org/aos/agrovoc#c_8130
IMMUNE RESPONSE
INFECTIOUS BURSAL DISEASE VIRUS
POULTRY
REPONSE IMMUNITAIRE
RESPUESTA INMUNOLOGICA
VACCIN
VACCINES
VACUNA
VIRUS BURSITE INFECTIEUSE
VIRUS BURSITIS INFECCIOSA
VITAMIN E
VITAMINA E
VITAMINE E
VOLAILLE
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Summary:The immunogenicity and protective capability of D, L-±-tocopheryl acetate (vitamin E) adjuvanted Newcastle disease (ND) + Infectious bursal disease (IBD) inactivated vaccine was evaluated in broiler chicks. Results showed that the vaccine supplemented with vitamin E induced more rapid and higher antibody response than control vaccines. Post challenge with virulent ND and IBD virus, absolute protection was recorded in chicks earlier vaccinated with ND + IBD vaccine containing adjuvant replaced with 20 and 10 per cent vit. E, respectively. Post challenge gross and histopathological lesions were minimum in-group vaccinated with vitamin E adjuvanted vaccine. Our results provide an evidence that vitamin E can be used efficiently as component of inactivated ND + IBD vaccine to induce protective immune response in birds.
Bibliography:L70
2012000082
ISSN:0250-4758