Contributions to toxicity of Cistus ladaniferus: Anatomicopathological alterations

The lesions induced by means of the oral administration of an hydroalcoholic extract of Cistus ladaniferus to rats were studied. The duration of the study and the doses used were similar to those described in the naturally occurring intoxication encountered in sheep. The lungs, liver and kidneys sho...

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Published inMedicina veterinaria (Barcelona, Spain) Vol. 3; no. 4
Main Authors Capo Marti, M, Nieto Martinez, J.M, Pizarro Diaz, M. (Universidad Complutense de Madrid (Spain). Facultad de Veterinaria), Bregante Ucedo, M
Format Journal Article
LanguageSpanish
Published 01.04.1986
Subjects
BOSQUE BAJO
ENFERMEDADES (TRACTO URINARIO)
ENFERMEDADES HEPATICAS
ENFERMEDADES RESPIRATORIAS
MALADIE DE L'APPAREIL URINAIRE
MALADIE DU FOIE
MALADIE RESPIRATOIRE
PATHOLOGIE
PATOLOGIA
PLANTAS TOXICAS
PLANTE TOXIQUE
RAT
RATA
TAILLIS SIMPLE
TOXICIDAD POR INGESTION
TOXICITE PAR INGESTION
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Summary:The lesions induced by means of the oral administration of an hydroalcoholic extract of Cistus ladaniferus to rats were studied. The duration of the study and the doses used were similar to those described in the naturally occurring intoxication encountered in sheep. The lungs, liver and kidneys show gross non specific lesions. The pulmonary lesions correspond microscopically to a catarrhal bronchopneumonia with descamation. The liver presents vacuolar cytoplasmic degeneration and areas of micronecrosis together with a perifocal inflammatory reaction with histiocytes, lymphocytes and plasma cells. The kidney shows a toxic nephrosis with granular casts and a focal interstitial nephritis
Bibliography:8700038
L74
ISSN:0212-8292