The sanitary-toxicological characteristic of a complex disinfectant - PMC

• Published in: Ehpizootologiya. Immunologiya. Farmakologiya. Sanitariya (Belarus) no. 2; pp. 61 - 65
• Main Authors: Bogush, A.A, Kamenskaya, T.N, Ivanov, V.E, Lukyanchik, S.A, Adamovich, L.P, Chernik, M.I., The National Academy of Sciences, Minsk (Belarus). The S.N.Vyshelesskij Inst. of Experimental Veterinary Medicine, Shablovskij, V.O, Tuchkovskaya, A.V, Vasyuchenok, N.N., Belarus State Univ., Minsk (Belarus)
• Format: Publication
• Language: Russian
• Published: 2007
• Subjects: ANIMAL DE LABORATOIRE; ANIMAL UTILEANIMAL UTILE; ANIMALES DE LABORATORIO; ANIMALES UTILESANIMALES UTILES; BARNS; BELARUS; DESINFECCION; DESINFECTANT; DESINFECTANTES; DESINFECTION; DISINFECTANTS; DISINFECTION; FLORA MICROBIANA; FLORE MICROBIENNE; GRANEROS; GRANGE; HIGIENE VETERINARIA; http://www.fao.org/aos/agrovoc#c_10397; http://www.fao.org/aos/agrovoc#c_16367; http://www.fao.org/aos/agrovoc#c_2331; http://www.fao.org/aos/agrovoc#c_29108000029108; http://www.fao.org/aos/agrovoc#c_33237; http://www.fao.org/aos/agrovoc#c_4126; http://www.fao.org/aos/agrovoc#c_7826; http://www.fao.org/aos/agrovoc#c_8205; http://www.fao.org/aos/agrovoc#c_825; HYGIENE VETERINAIRE; LABORATORY ANIMALS; MICROBIAL FLORA; TOXICIDAD; TOXICITE; TOXICITY; USEFUL ANIMALS; VETERINARY HYGIENE

The description of antimicrobial properties and toxicities of a complex disinfectant drug PMC is done. The selected composition of the preparation N7 (the working name PMC ) at loading of test microbes 0,5 billion, expositions of 30 minutes, in dilution of 0,01% possessed by bactericidal activity, including albuminous loading. To culture Mycobacterium terra bactericidal action was shown in concentration of the preparation of 0,025%. Acute toxicity of PMC in experience on white mice at intragastric introduction has made 2500 mg/kg of body weight. Acute inhalation toxicity of the preparation has made LK50 -100 ml/cubic m. Chronic intragastric and inhalation toxicity of the preparation PMC in experience on white mice was absent. The working solution (3%) preparation PMC - possesses weak local-irritating property and not sensitizes of the rabbit’s organism during experience. The complex disinfectant preparation PMC in concentration of 0,1% possesses bactericidal properties in relation to the cultures allocated from a rabbit-hutch (intestinal stick, protey, staphilococcuses)