Tracheal restoration in dogs with umbilical cord membrane of bovine preserved in glicerin

The viability of the use the bovine umbilical membrane preserved in 98% glycerin implanted in the cervical trachea was studied. Seven adult mongrel dogs, three males and four females weighting 6 to 14 kg, were used. After the usual anesthesia protocol and asseptic technique, three tracheal rings wer...

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Published inBrazilian journal of veterinary research and animal science Vol. 37; no. 4; pp. 316 - 320
Main Authors Alexandre Mazzanty, Ney Luis Pippi, Alceu Gaspar Raiser, Dominguita Lühers Graça, Aron Ferreira da Silveira, Duvaldo Eurides, Renato Xavier Faria, Gentil Ferreira Gonçalves, Alonso Gabriel Pereira Guedes, Marilaine Vistué Rios
Format Journal Article
LanguagePortuguese
Published Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia 01.01.2000
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Summary:The viability of the use the bovine umbilical membrane preserved in 98% glycerin implanted in the cervical trachea was studied. Seven adult mongrel dogs, three males and four females weighting 6 to 14 kg, were used. After the usual anesthesia protocol and asseptic technique, three tracheal rings were partially removed for implantation of a segment of the umbilical membrane. The animals were observed during 30 days and then reoperated for macroscopic observations and for fragment collection for histological evaluation. It occurred a repair of the tracheal lesion, with formation of granulation tissue rich in collagen fibers linking the extremities of the tracheal cartilages. Epithelial migration over the tracheal surface was also seen. It is concluded that the segment of the bovine umbilical cord preserved in 98% glycerin can be used in the repair of tracheal defects. It offers a temporary support for granulation tissue formation and epithelization in the implanted area. A viabilidade do uso da membrana do cordão umbilical de bovinos, conservada em glicerina, foi estudada na reparação da traquéia cervical de cães. Foram utilizados sete cães, adultos, três machos e quatro fêmeas, sem raça definida com peso variando de 6 a 14 kg. Três anéis traqueais (1,5 x 2,5 cm) foram removidos parcialmente para implantação de um segmento de membrana umbilical. Os animais foram observados por um período de 30 dias de pós-operatório (PO), quando foram reoperados para observações macroscópicas e coleta de amostras para avaliação histológica. Ocorreu reparação da lesão traqueal, com formação de tecido de granulação, rico em fibras colágenas unindo as extremidades das cartilagens traqueais do defeito e migração epitelial na superfície traqueal. A membrana do cordão umbilical de bovino conservado em glicerina pode ser utilizada na reparação de defeitos traqueais, pois oferece suporte temporário para a formação de tecido de granulação e permite a epitelização na região do implante.
Bibliography:http://revistas.usp.br/bjvras/article/view/5806
ISSN:1413-9596
1678-4456