Case report of an autosomal dominant polycystic kidney disease in a Persian cat

Polycystic kidney disease in Persian cats closely resembles the autosomal polycystic kidney disease in human beings. Both diseases are inherited as autosomal dominant traits. They are characterized by the development and enlargment of cysts in the renal cortex and medulla resulting in progressive re...

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Bibliographic Details
Published inAnnales de médecine vétérinaire Vol. 145; no. 2
Main Authors Vanloubbeeck, Y, Desmecht, D, Cassart, D, Coignoul, F. (Universite de Liege, Sart Tilman (Belgium). Faculte de medecine veterinaire. service de pathologie generale)
Format Journal Article
LanguageFrench
Published 01.03.2000
Subjects
CATS
CHAT
DIAGNOSIS
DIAGNOSTIC
DIAGNOSTICO
ENFERMEDADES HUMANAS
ENFERMEDADES RENALES
GATO
HUMAN DISEASES
KIDNEY DISEASES
KIDNEYS
MALADIE DE L'HOMME
MODELE
MODELOS
NEPHROPATHIE
REIN
RINONES
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Summary:Polycystic kidney disease in Persian cats closely resembles the autosomal polycystic kidney disease in human beings. Both diseases are inherited as autosomal dominant traits. They are characterized by the development and enlargment of cysts in the renal cortex and medulla resulting in progressive renomegaly. Finally, both diseases usually are accompanied by renal failure late in life. The marked clinical and morphological similarities of APKD in Persian cats and the human disease, as well as the autosomal dominant inheritance pattern, suggest that the feline condition is a potential model for the study of APKD in humans.
Bibliography:L74
2000001012
ISSN:0003-4118