Evaluation of Some Lectins as Anti-protozoal Agents
Ten lectins from different sources were screened for cytotoxic activity against Acanthamoeba sp. (a keratitis-causing amoeba) and Tetrahymena pyriformis (a ciliate). Lectins from Schefflera odorata ("lima-lima" plant) [molecular weight = 271 kDa], Swietenia macrophylla (large leaf mahogany...
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Main Authors | , , , , |
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Format | Publication |
Language | English |
Published |
Asian Network for Scientific Information, Pakistan
2005
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Subjects | |
Online Access | Get more information |
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Summary: | Ten lectins from different sources were screened for cytotoxic activity against Acanthamoeba sp. (a keratitis-causing amoeba) and Tetrahymena pyriformis (a ciliate). Lectins from Schefflera odorata ("lima-lima" plant) [molecular weight = 271 kDa], Swietenia macrophylla (large leaf mahogany) [molecular weight = 295 kDa] and Lenzites sp. (a mushroom) [molecular weight = 184 kDa] were found to possess high cytotoxic activity against the test organisms. These results indicate that lectins may be further exploited as potential chemotherapeutics against certain parasitic diseases. |
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Bibliography: | http://www.scialert.net/pdfs/jms/2005/31-34.pdf http://www.doaj.org/doaj?func=openurl&genre=article&issn=16824474&date=2005&volume=5&issue=1&spage=31 |