The Role of Three Dimensional Geometric Descriptors of Selected PAHS on Inducing Mortality in Juvenile Angel Fish (Pterophyllum scalare)

• Main Authors: A. Karami-Varnamkhasti, P. Eghtesadi-Araghi, H. Negarestan, O. Ranaei Siadat, A. Maghsoudlou
• Format: Publication
• Language: English
• Published: Asian Network for Scientific Information, Pakistan 2008
• Subjects: geometric; mortality; PAHs; Pterophyllum scalare; QSAR

Juvenile angelfish (Pterophyllum scalare) was exposed to six different concentrations of Naphthalene, Anthracene, Phenanthrene and Pyrene for a period of 132 h. Mortalities were recorded each 12 h and an average of total mortalities for three replicates of each PAHs was designated as the endpoint of toxicity for angelfishes. This parameter correlated with geometric descriptors (length, width, thickness, length/breadth ratio, molecular volume and molecular surface area), physiochemical descriptors (molar volume, molecular weight, octanol-water partition coefficient and boiling point) and an electronic descriptor (resonance energy). The regression equations showed the significant correlation for three dimensional geometric descriptors, physiochemical descriptors and resonance energy versus mortality. These results indicate that at the range of log Kow<=5.2, raising three dimensional geometric descriptors values will result in more mortality.