3,6-ketal and enol ether macrolide antibiotics

This invention relates to compounds of formulas 1 and 2 and to pharmaceutically acceptable salts and solvates thereof, wherein X, X , R , R , R , R and R are as defined herein. The compounds of formulas 1 and 2 may be useful in the treatment of bacterial, parasitic and protozoal infections, as well...

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Bibliographic Details
Main Authors KRISTIN M. LUNDY, MARTHA L. MINICH, PETER BERTINATO, SUBAS M. SAKYA, HENGMIAO CHENG
Format Patent
LanguageEnglish
Published 12.10.2000
Edition7
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:This invention relates to compounds of formulas 1 and 2 and to pharmaceutically acceptable salts and solvates thereof, wherein X, X , R , R , R , R and R are as defined herein. The compounds of formulas 1 and 2 may be useful in the treatment of bacterial, parasitic and protozoal infections, as well as disorders related to bacterial, parasitic and protozoal infections, in mammals, fish and birds. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and 2 and to methods of treating bacterial, parasitic and protozoal infections by administering the compounds of formula 1 and 2.
Bibliography:Application Number: ZA19990001664