Humanized anti-human fas antibody

The invention provides humanised anti-human Fas antibodies capable of inducing apoptosis in cells expressing Fas and which are useful in the treatment of autoimmune disease and chronic rheumatoid arthritis. In addition, the invention provides DNA encoding the variable regions of the H and L chain of...

Full description

Saved in:
Bibliographic Details
Main Authors TOHRU TAKAHASHI, HIDEYUKI HARUYAMA, KAORI NAKAHARA, SHIN YONEHARA, NOBUFUSA SERIZAWA
Format Patent
LanguageEnglish
Published 28.09.1998
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:The invention provides humanised anti-human Fas antibodies capable of inducing apoptosis in cells expressing Fas and which are useful in the treatment of autoimmune disease and chronic rheumatoid arthritis. In addition, the invention provides DNA encoding the variable regions of the H and L chain of such antibodies and methods for humanising antibodies.
Bibliography:Application Number: ZA19980002371