Soluble polypeptidic fragments of lag-3 protein method of production thereof therapeutic composition anti-idiotype antibodies
Soluble polypeptide fraction consisting of all or part of one at least one of the four immunoglobulin-type extracellular LAG-3 protein domains (amino acids 1-159, 160-230, 240-330 and 331-412 of the SEQ ID NO:1 sequence) or consisting of one peptide sequence derived from these domains by replacement...
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Main Authors | , , , |
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Format | Patent |
Language | English |
Published |
05.11.1996
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | Soluble polypeptide fraction consisting of all or part of one at least one of the four immunoglobulin-type extracellular LAG-3 protein domains (amino acids 1-159, 160-230, 240-330 and 331-412 of the SEQ ID NO:1 sequence) or consisting of one peptide sequence derived from these domains by replacement, addition or deletion of one or more amino acids. The fraction of the invention has a specificity at least equal to that of LAG-3 in relation to its ligand. |
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Bibliography: | Application Number: ZA19950003629 |