MEDICAMENT FORMULATION
A medicament formulation of intravenous injection comprising a medicinally active compound, a lipid phase, an emulsifier and water, the lipid phase being present in up to about 30% by weight, the emulsifier being present in about 0.1 to 10% by weight, and water being present up to 100%, the lipid ph...
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Main Author | |
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Format | Patent |
Language | English |
Published |
26.06.1985
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Edition | 4 |
Subjects | |
Online Access | Get full text |
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Summary: | A medicament formulation of intravenous injection comprising a medicinally active compound, a lipid phase, an emulsifier and water, the lipid phase being present in up to about 30% by weight, the emulsifier being present in about 0.1 to 10% by weight, and water being present up to 100%, the lipid phase containing up to about 50% by weight of a sparingly soluble medicinally active compound, and consisting essentially of (a) at least one ester principally of at least one medium chain-length fatty acid, or (b) a mixture of at least one ester principally of at least one medium chain-length fatty acid with at least one vegetable or animal oil, the mixture containing at least 10% by weight of the ester principally of the medium chain-length fatty acid, or (c) at least one ester principally of at least one medium chain-length fatty acid, at least one vegetable or animal oil, or a mixture thereof, in combination with 0.3 to 200% by weight of benzyl alcohol based on the content of lipid or oil. A greater amount of medicinal agent can be administered in a reduced total volume of injectable liquid. |
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Bibliography: | Application Number: ZA19840008375 |