14,15BETA-EPOXYCARDENOLIDE-AND 14,15BETA-EPOXYBUFADIENOLIDE GLYCOSIDES AND PROCESS FOR THEIR PREPARATION

Cardioactive 3 beta -hydroxy-14,15 beta -epoxy-5 beta -cardenolide-or -5 beta -bufadienolide-glucosides and rhamnosides. A method for making these compounds by reacting the corresponding 14-anhydrocardenolides or 14-anhydrobufadienolides with an acylhalopyranose, reacting the resultant acylated pyra...

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Bibliographic Details
Main Authors RADSCHEIT K, STACHE U, LINDNER E, HAEDE W, FRITSCH W
Format Patent
LanguageEnglish
Published 25.04.1973
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Summary:Cardioactive 3 beta -hydroxy-14,15 beta -epoxy-5 beta -cardenolide-or -5 beta -bufadienolide-glucosides and rhamnosides. A method for making these compounds by reacting the corresponding 14-anhydrocardenolides or 14-anhydrobufadienolides with an acylhalopyranose, reacting the resultant acylated pyranoside with a hypohalous acid to form the corresponding halohydrin, and epoxidizing the halohydrin with a base.
Bibliography:Application Number: ZA19720005058