IMPROVEMENTS RELATING TO A NOVEL CINNAMIC ACID AMIDE

New N-(4-chloro)cinnamoyl-(4'-hydroxy)-piperazine is prepared by a) reacting a cinnamic acid deriv. of formula p-Cl-C6H4-CH=CH-COX (in which X is OH, NH, mono- or dialkylamino, or a reactive group) with 4-hydroxypiperidine, or a reactive deriv. of 4-hydroxypiperidine; b) or by reacting a cpd. o...

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Bibliographic Details
Main Authors ECKENFELS A, KLEEMAN M, DAJHMS G, GRELL W, MACHLEIDT H
Format Patent
LanguageEnglish
Published 24.02.1971
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Summary:New N-(4-chloro)cinnamoyl-(4'-hydroxy)-piperazine is prepared by a) reacting a cinnamic acid deriv. of formula p-Cl-C6H4-CH=CH-COX (in which X is OH, NH, mono- or dialkylamino, or a reactive group) with 4-hydroxypiperidine, or a reactive deriv. of 4-hydroxypiperidine; b) or by reacting a cpd. of formula: (in which R is lower alkyl or (R1)3-P=CH-, where R1 is aryl or alkyl) with 4-chlorobenzaldehyde.
Bibliography:Application Number: ZA19700003465