6-PYRIMIDIN-ISOINDOLE DERIVATIVE AS ERK1/2 INHIBITOR

This invention relates to the compound (2R)-2-(6-{5-chloro-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1 -oxo-2,3-dihydro-1 H-isoindol-2-yl)-N-[(1 S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide, and in particular to novel physical forms of the compound, a process for preparing the compound and s...

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Main Authors BAGULEY, Paul, Anthony, WILSHER, Nicola, Elizabeth, READER, Michael, ADAMCZYK, Bozena, Ewa, MELLING, Robert, Craig, LINDLEY, Colin, Thomas, SCARATI, Mirka, SAUNDERS, Mark, Henry
Format Patent
LanguageEnglish
Published 30.05.2024
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Summary:This invention relates to the compound (2R)-2-(6-{5-chloro-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1 -oxo-2,3-dihydro-1 H-isoindol-2-yl)-N-[(1 S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide, and in particular to novel physical forms of the compound, a process for preparing the compound and synthetic intermediates for use in the process, and novel formulations containing the compound, as well as therapeutic uses of the compound.
Bibliography:Application Number: ZA20190007484