PERSONALISED IMMUNOGENIC PEPTIDE IDENTIFICATION PLATFORM

The disclosure relates to methods of identifying fragments of a polypeptide that are immunogenic for a specific human subject, methods of preparing personalised pharmaceutical compositions comprising such polypeptide fragments, human subject-specific pharmaceutical compositions comprising such polyp...

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Main Authors LORINCZ, Orsolya, LISZIEWICZ, Julianna, MEGYESI, Mónika, MOLNÁR, Levente, TOKE, Eniko R, CSISZOVSZKI, Zsolt, TOTH, József, SOMOGYI, Eszter, PÁNTYA, Katalin
Format Patent
LanguageEnglish
Published 31.01.2024
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Summary:The disclosure relates to methods of identifying fragments of a polypeptide that are immunogenic for a specific human subject, methods of preparing personalised pharmaceutical compositions comprising such polypeptide fragments, human subject-specific pharmaceutical compositions comprising such polypeptide fragments, and methods of treatment using such compositions. The methods comprise identifying a fragment of the polypeptide that binds to multiple HLA of the subject.
Bibliography:Application Number: ZA20190004725