BINDING MOLECULES THAT INHIBIT CANCER GROWTH

The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds an extracellular part of a membrane associated member of the epidermal growth factor (EGF) receptor family and an extracellular part of a membrane ass...

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Main Authors ROBERT GERHARDUS JACOB VRIES, JOHANNES CAROLUS CLEVERS, EDUARD BATLLE, TON LOGTENBERG, MARK THROSBY, BRAM HERPERS
Format Patent
LanguageEnglish
Published 26.08.2020
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Summary:The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds an extracellular part of a membrane associated member of the epidermal growth factor (EGF) receptor family and an extracellular part of a membrane associated member of a WNT signaling pathway. Further provided are various cells and assays that are helpful in the production of the proteins, antibodies and cells.
Bibliography:Application Number: ZA20180002758