BICYCLIC¿FUSED HETEROARYL OR ARYL COMPOUNDS AS IRAK4 MODULATORS

Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula IIc to IIi, IIl to IIv or IIx as defined in the claims. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermedia...

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Main Authors ZAPF, Christoph Wolfgang, HEPWORTH, David, STROHBACH, Joseph Walter, PAPAIOANNOU, Nikolaos, WRIGHT, Stephen Wayne, LEE, Arthur, LEE, Katherine Lin, TRZUPEK, John, David, LOVERING, Frank Eldridge, MATHIAS, John Paul, ALLAIS, Christophe, Philippe, HAN, Seungil, GAVRIN, Lori Krim, DEHNHARDT, Christoph Martin, OWEN, Dafydd, Rhys, SAIAH, Eddine
Format Patent
LanguageEnglish
Published 31.07.2019
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Summary:Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula IIc to IIi, IIl to IIv or IIx as defined in the claims. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
Bibliography:Application Number: ZA20180000388