ANTIBODIES TO CD40

Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40. Such antibodies optionally comprise Fc regions with enhanced specificity for FcγRIIb. The invention also provides methods of treatment of cancer or chronic infection by administering the antibodie...

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Bibliographic Details
Main Authors STEVENS, Brenda L, BARNHART, Bryan C, DEVAUX, Brigitte, YAMNIUK, Aaron P, OKADA, Shannon L
Format Patent
LanguageEnglish
Published 28.08.2019
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Summary:Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40. Such antibodies optionally comprise Fc regions with enhanced specificity for FcγRIIb. The invention also provides methods of treatment of cancer or chronic infection by administering the antibodies of the invention to a subject in need thereof.
Bibliography:Application Number: ZA20170008704