METHYL-AND TRIFLUOROMETHYL-SUBSTITUTED PYRROLOPYRIDINE MODULATORS OF RORC2 AND METHODS OF USE THEREOF

The present invention provides methyl- and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharma...

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Main Authors MENTE, Scot Richard, ZHANG, Liying, TRZUPEK, John David, ZAMARATSKI, Edouard, XING, Li, FLICK, Andrew Christopher, JONES, Peter, SCHNUTE, Mark Edward, WENNERSTÅL, Göran Mattias, KAILA, Neelu, VAZQUEZ, Michael L
Format Patent
LanguageEnglish
Published 18.12.2019
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Summary:The present invention provides methyl- and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.
Bibliography:Application Number: ZA20170006119