2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, ITS PREPARATION, DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

• Main Authors: CARL ZWICKER, SIMON PEGG, YUEGANG ZHANG, CHRISTOPHER JOHN DAVIS, DAMIEN FRAYSSE, JOHN STUDLEY, TAPAN SANGHVI, DAVID MATTHEW SHAW, MANINDER PANESAR, NAZIHA ALEM, ALES MEDEK, GORKA ETXEBARRIA I JARDI, JOANNE PINDER, FRANCOISE PIERARD, JEAN-DAMIEN CHARRIER, MICHAEL WALDO
• Format: Patent
• Language: English
• Published: 27.11.2019

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention.The compounds of this invention have formula I-A or I-B:wherein the variables are as defined herein.