SPIRO-OXAZOLONES

The present invention provides spiro-oxazolones, which act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The present compounds are useful as therapeutics acting peripherally and...

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Bibliographic Details
Main Authors RUNTZ-SCHMITT, Valerie, FASCHING, Bernhard, DOLENTE, Cosimo, SCHNIDER, Patrick
Format Patent
LanguageEnglish
Published 25.05.2022
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Summary:The present invention provides spiro-oxazolones, which act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The present compounds are useful as therapeutics acting peripherally and centrally in the conditions of inappropriate secretion of vasopressin, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, aggressive behavior and phase shift sleep disorders, in particular jetlag.
Bibliography:Application Number: ZA20160003221