SHIP1 MODULATORS AND METHODS RELATED THERETO

n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulati...

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Main Authors RUDONG SHAN, LLOYD F MACKENZIE, VLADIMIR KHLEBNIKOV, THOMAS B MACRURY, CURTIS HARWIG, JEFFERY R RAYMOND, DAVID BOGUCKI, JEREMY D PETTIGREW
Format Patent
LanguageEnglish
Published 29.11.2017
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Summary:n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Compositions comprising a compound of formula (I) in combination with a pharmaceutically acceptable carrier or diluent are also disclosed, as are methods of SHIP1 modulation by administration of such compounds to an animal in need thereof.
Bibliography:Application Number: ZA20150004477