TETRAHYDROPYRAZOLOPYRIMIDINE COMPOUNDS

Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.

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Main Authors HANS HANSEN, ROCH BOIVIN, SRIDHAR NARAYAN, LYNN D HAWKINS, SALLY ISHIZAKA, SHAWN SCHILLER, TAKASHI SATOH, ATSUSHI ENDO, MATTHEW MACKEY, ERIC CARLSON
Format Patent
LanguageEnglish
Published 25.05.2016
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Summary:Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
Bibliography:Application Number: ZA20140009273