OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION

The present invention relates to compounds of formula (I) and (IA): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various d...

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Main Authors BARTOLOZZI ALESSANDRA, BOSANAC TODD, RIETHER DORIS, LIU WEIMIN, ZINDELL RENEE M, OLAGUE ALAN, DE LOMBAERT STEPHANE, LOKE PUI LENG, HUBER JOHN D, WU LIFEN, TYE HEATHER, DINES JONATHON ALAN, CHEN ZHIDONG, MORWICK TINA MARIE
Format Patent
LanguageEnglish
Published 27.08.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of formula (I) and (IA): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
Bibliography:Application Number: ZA20130001747