STABLE GROWTH HORMONE COMPOUNDS

• Main Authors: THYGESEN PETER, SCHIODT CHRISTINE BRUUN SCHIODT, CHEN JIANHE, NORSKOV-LAURITSEN LEIF, DEMUTH HELLE
• Format: Patent
• Language: English
• Published: 24.04.2013
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to growth hormone (GH) compounds having additional disulphide bridges and at least one additional single point mutation making the compounds resistant to proteolytic degradation.