STABLE GROWTH HORMONE COMPOUNDS

The present invention relates to growth hormone (GH) compounds having additional disulphide bridges and at least one additional single point mutation making the compounds resistant to proteolytic degradation.

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Bibliographic Details
Main Authors THYGESEN PETER, SCHIODT CHRISTINE BRUUN SCHIODT, CHEN JIANHE, NORSKOV-LAURITSEN LEIF, DEMUTH HELLE
Format Patent
LanguageEnglish
Published 24.04.2013
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to growth hormone (GH) compounds having additional disulphide bridges and at least one additional single point mutation making the compounds resistant to proteolytic degradation.
Bibliography:Application Number: ZA20120005385