1,3-disubstituted indole derivatives for use as PPAR modulators

Compounds are described that are active on PPARs, including pan-active compounds and compounds selective for any one or any two of PPARalpha, PPARalpha and PPARdelta. Also described are methods of use of the compounds in treating various diseases.

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Bibliographic Details
Main Authors WANG, WEIRU, SHI, SHENGHUA, LEE, BYUNGHUN, LIN, JACK, WOMACK, PATRICK, ARTIS, DEAN R, ZHANG, CHAO, ZUCKERMAN, REBECCA, IBRAHIM, PRABHA N
Format Patent
LanguageEnglish
Published 31.12.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds are described that are active on PPARs, including pan-active compounds and compounds selective for any one or any two of PPARalpha, PPARalpha and PPARdelta. Also described are methods of use of the compounds in treating various diseases.
Bibliography:Application Number: ZA20080002007