Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands

The present invention provides aminoaryl sulphonamide derivatives of formula (I), useful in the treatment of a CNS disorder related to or affected by the 5-HT6 receptor. Pharmacological profiles of these components include high affinity binding with 5-HT6 receptors along with good selectivity toward...

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Main Authors KANDIKERE, NAGARAJ VISHWOTTAM, SHIRSATH, VIKAS SHREEKRISHNA, JASTI, VENKATESWARLU, VISHWAKARMA, SANTOSH, KOTA, SRINIVASULU, RAMAKRISHNA, VENKATA SATYA NIROGI, KAMBHAMPATI, RAMA SASTRI
Format Patent
LanguageEnglish
Published 25.02.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides aminoaryl sulphonamide derivatives of formula (I), useful in the treatment of a CNS disorder related to or affected by the 5-HT6 receptor. Pharmacological profiles of these components include high affinity binding with 5-HT6 receptors along with good selectivity towards the receptor. The present invention also includes stereoisomers, the salts, methods of preparation and medicine containing the aminoaryl sulphonamide derivatives.
Bibliography:Application Number: ZA20080001276