Aminophenyl derivatives as selective androgen receptor modulators

Disclosed herein is a novel class of aminophenyl compounds having the structure: wherein R1 is cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or prevention of conditions relating thereto.

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Bibliographic Details
Main Authors BADALASSI, FABRIZIO, SCHLIENGER, NATHALIE, THYGESEN, MIKKEL BOAS, LUND, BIRGITTE WINTHER, PAWLAS, JAN, LEWINSKY, RASMUS, OLSSON, ROGER
Format Patent
LanguageEnglish
Published 31.12.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed herein is a novel class of aminophenyl compounds having the structure: wherein R1 is cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or prevention of conditions relating thereto.
Bibliography:Application Number: ZA20070005458