2-acylaminothiazole derivatives

The disclosure relates to 2-acylamino-thiazole derivative compounds of the formula (I), wherein the variables are as defined in the specification, for use as a medicament. The compounds are A2A-receptor legends and are useful in the treatment of neurological and psychiatric disorders where an A2A-re...

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Bibliographic Details
Main Authors MIKKELSEN, GITTE, LARSEN, MOGENS, BANG-ANDERSEN, BENNY, SAMS, ANETTE GRAVEN
Format Patent
LanguageEnglish
Published 29.10.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosure relates to 2-acylamino-thiazole derivative compounds of the formula (I), wherein the variables are as defined in the specification, for use as a medicament. The compounds are A2A-receptor legends and are useful in the treatment of neurological and psychiatric disorders where an A2A-receptor is implicated, particularly diseases such as Parkinson's Disease (PD), Alzheimer's Disease, Huntington's disease, cerebral ischemia, haemorrhagic stroke, neonatal ischemia and hypoxia, subarachnoid haemorrhage, traumatic brain injury, cardiac arrest, Multiple Sclerosis, depression and psychosis.
Bibliography:Application Number: ZA20070002325