Method for the humanization of antibodies and humanized antibodies thereby obtained

A humanized anti-NGF antibody having one or more complementary determining regions (CDRs) selected from a heavy chain first CDR comprising the amino acid sequence GFSLTNNNVNW, a heavy chain second CDR comprising the amino acid sequence GVWAGGATDYNSALKS, a heavy chain third CDR comprising the amino a...

Full description

Saved in:
Bibliographic Details
Main Authors CATTANEO, ANTONINO, COVACEUSZACH, SONIA, LAMBA, DORIANO
Format Patent
LanguageEnglish
Published 26.08.2009
Subjects
CHEMISTRY
INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
Online AccessGet full text

Cover

More Information
Summary:A humanized anti-NGF antibody having one or more complementary determining regions (CDRs) selected from a heavy chain first CDR comprising the amino acid sequence GFSLTNNNVNW, a heavy chain second CDR comprising the amino acid sequence GVWAGGATDYNSALKS, a heavy chain third CDR comprising the amino acid sequence DGGYSSSTLYAMDA, a light chain first CDR comprising the amino acid sequence RASEDIYNALA, a light chain second CDR comprising the amino acid sequence HT and a light chain third CDR sequence comprising the amino acid sequence QHYFHYPRT.
Bibliography:Application Number: ZA20060005200