Isoquinoline derivatives

Isoquinoline derivatives of the general formula (I) in which X, Y, Z, R1, R2, and n are as defined in Patent Claim ( 1 ), and physiologically acceptable salts or solvates thereof, are integrin inhibitors and can be employed for combating thromboses, cardiac infarction, coronary heart diseases, arter...

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Main Authors SIMON GOODMAN, DIRK WEBER, DIRK GOTTSCHLING, GEORGETTE THUMSHIRN, MATTHIAS WIESNER, HORST KESSLER
Format Patent
LanguageEnglish
Published 05.07.2005
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Isoquinoline derivatives of the general formula (I) in which X, Y, Z, R1, R2, and n are as defined in Patent Claim ( 1 ), and physiologically acceptable salts or solvates thereof, are integrin inhibitors and can be employed for combating thromboses, cardiac infarction, coronary heart diseases, arteriosclerosis, inflammation, tumours, osteoporosis, infections and restenosis after angioplasty or in pathological processes which are maintained or propagated by angiogenesis.
Bibliography:Application Number: ZA20040008027