SUBSTITUTED BICYCLIC HETEROCYCLES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTIOBESITY AND HYPOCHOLESTEROLEMIC AGENTS

• Main Authors: RANJAN, CHAKRABARTI, KALCHAR, SHIVARAMAYA, RAJAGOPALAN, RAMANUJAM, ASHOK, CHANNAVEERAPPA BAJJI, LOHRAY, VIDYA BHUSHAN, LOHRAY, BRAY BHUSHAN, GURRAM, RANGA MADHAVAN
• Format: Patent
• Language: English
• Published: 19.07.2005
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel ß-aryl-α-oxysubstituted alkylcarboxylic acids of general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. Ovaj pronalazak se odnosi na nova antigojazna i hipoholesterolemijska jedinjenja, njihove derivate, njihove analoge, njihove tautomerne oblike, njihove stereoizomere, njihove polimorfe, njihove farmaceutski prihvatljive soli, njihove farmaceutski prihvatijive rastvarače i farmaceutski prihvatljive smeše, koje ih sadrže. Preciznije, ovaj pronalazak se odnosi na nove Гџ-aril-α-oksisupstituisane alkilkarboksilne kiseline opšte formule (I), njihove derivate, njihove analoge, njihove tautomerne oblike, njihove steroizomere, njihove polimorfe, njihove farmaceutski prihvatljive soli, njihove farmaceutski prihvatljive rastvarače i farmaceutski prihvatljive smeše, koje ih sadrže.[The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel Гџ-aryl-α-oxysubstituted alkylcarboxylic acids of general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.