NOVEL FORMS OF PRAVASTATIN SODIUM
New polymorphic forms of pravastatin sodium are provided. Each of the new forms is selectively obtained by crystallization from different solvent systems, each solvent system having a protic component, and by controlling the rate of crystallization through temperature. The new polymorphic forms are...
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Main Authors | , , , |
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Format | Patent |
Language | English |
Published |
28.11.2005
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Subjects | |
Online Access | Get full text |
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Summary: | New polymorphic forms of pravastatin sodium are provided. Each of the new forms is selectively obtained by crystallization from different solvent systems, each solvent system having a protic component, and by controlling the rate of crystallization through temperature. The new polymorphic forms are suitable for use as active substances of pharmaceutical dosage forms for reduction of serum cholesterol levels in the bloodstream.
Obezbedjeni su novi polimorfni oblici natrijum pravastatina. Svaki od novih oblika je dobijen selektivno kristalizacijom iz različitih sistema rastvarača, svaki sistem rastvarača ima protičku komponentu, i kontrolom stope kristalizacije putem temperature. Novi polimorfni oblici pogodni su za upotrebu kao aktivne supstance farmaceutskih oblika doza za redukciju nivoa serumskog holesterola u krvotoku.[New polymorphic forms of pravastatin sodium are provided. Each of the new forms is selectively obtained by crystallization from different solvent systems, each solvent system having a protic component, and by controlling the rate of crystallization through temperature. The new polymorphic forms are suitable for use as active substances of pharmaceutical dosage forms for reduction of serum cholesterol levels in the bloodstream. |
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Bibliography: | Application Number: YUP45202 |