PROCESS FOR OBTAINING THIENOPYRIDINE DERIVATIVES

This invention relates to a process for the preparation of compounds having the general formula: (I) in which: R1 represents a hydrogen atom, an optionaly substituted alkyl, aryl or aralkyl radical; R2 and R3 are the same or different and represent independently a hydrogen atom, a lower alkyl, aryl...

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Bibliographic Details
Main Authors BOUSQUET A, BRAYE E
Format Patent
LanguageEnglish
Published 31.08.1982
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention relates to a process for the preparation of compounds having the general formula: (I) in which: R1 represents a hydrogen atom, an optionaly substituted alkyl, aryl or aralkyl radical; R2 and R3 are the same or different and represent independently a hydrogen atom, a lower alkyl, aryl or heterocyclic radical; and R4 represents a hydrogen atom or an alkyl, cycloalkyl, alkoxy carbonyl, carboxy, aryl or heterocyclic radical, comprising reacting a compound having the formula: (II) in which R1, R2 and R3 are as defined above, with a compound having the formula: (III) in which R4 is as defined above; X is a halogen atom, or an optionally substituted alkoxy, thioalkyl or amino group; and Y represents an optionally substituted alkoxy, thioalkyl or amino group, or a group of the formula: in which R is a lower alkyl or aryl radical; or both the groups X and Y, together with the carbon atom to which they are attached, form a 6-membered hexahydro-S-triazinic, trioxannic or trithianic heterocyclic nucleus, in an inert solvent, at a temperature between 0 DEG and 150 DEG C. and in an anhydrous medium, and, if desired, liberating the free base.
Bibliography:Application Number: YU19780001482