COMPOSITION AND METHOD FOR DERMAL AND TRANSDERMAL ADMINISTRATION OF A CYTOKINE

A composition for transdermal administration of a cytokine is described. The composition includes a conjugate composed of a cytokine, such as an interferon, and at least one fatty acid moiety covalently attached to the cytokine. The conjugate has enhanced cutaneous delivery relative to the cytokine...

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Bibliographic Details
Main Authors ATTAH-POKU, SAM, KWADWO, FOLDVARI, MARIANNA
Format Patent
LanguageEnglish
French
Published 10.09.1999
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A composition for transdermal administration of a cytokine is described. The composition includes a conjugate composed of a cytokine, such as an interferon, and at least one fatty acid moiety covalently attached to the cytokine. The conjugate has enhanced cutaneous delivery relative to the cytokine alone. L'invention concerne une composition permettant l'administration transdermique d'une cytokine. La composition comprend un conjugué composé d'une cytokine, telle qu'un interféron, et au moins un fragment d'acide gras lié de manière covalente à la cytokine. Le conjugué présente un taux de pénétration cutanée amélioré en comparaison de la cytokine seule.
Bibliography:Application Number: WO1998CA01192