A METHOD OF IMPROVED MIXING IN ROLLER BOTTLES

A method for enhancing the mixing of materials in roller bottle by the introduction of controlled axial and cross-sectional flow perturbations is disclosed. The effectiveness of the method is demonstrated by achieving higher efficiency in cell culturing and virus propagation in roller bottles by int...

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Bibliographic Details
Main Authors SEARLES, JAMES, A, MUZZIO, FERNANDO, J, BRAMBLE, JOYE, L
Format Patent
LanguageEnglish
French
Published 14.05.1999
Edition6
Subjects
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:A method for enhancing the mixing of materials in roller bottle by the introduction of controlled axial and cross-sectional flow perturbations is disclosed. The effectiveness of the method is demonstrated by achieving higher efficiency in cell culturing and virus propagation in roller bottles by introducing controlled flow perturbations during the process. L'invention concerne un procédé permettant d'améliorer le mélange de substances dans une bouteille pour agitateur rotatif, ce procédé consistant à introduire de manière régulée des perturbations selon des écoulements axial et transversal. L'efficacité de ce procédé se traduit par un rendement amélioré des mises en culture cellulaire et une meilleure propagation virale dans les bouteilles pour agitateur rotatif, grâce à l'introduction des perturbations susmentionnées au cours du processus.
Bibliography:Application Number: WO1998US22729