SPERM SPECIFIC ANTIGENS 4.1 AND 6.7, DNA ENCODING THEM AND CONTRACEPTIVE VACCINES COMPRISING SAID SPERM ANTIGENS

• Main Authors: VAN DUIN, MARCEL, GROOTENHUIS, ARIJ, JAN, AITKEN, ROBERT, JOHN
• Format: Patent
• Language: English; French
• Published: 30.12.1998
• Edition: 6
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present invention is directed to mammalian sperm specific proteins 4.1 and 6.7, and nucleotide sequences encoding said proteins, as well as pharmaceutical formulations, in particular vaccines comprising said proteins. The proteins 4.1 and 6.7 are sperm specific and can be used in a vaccine to prevent or reduce fertility in subjects. Cette invention concerne des protéines 4,1 et 6,7 spécifiques du sperme de mammifères, les séquences nucléotidiques codant ces protéines ainsi que des formulations pharmaceutiques, plus particulièrement des vaccins contenant lesdites protéines. Les protéines 4,1 et 6,7 sont spécifiques du sperme et peuvent être utilisées dans un vaccin pour bloquer ou réduire la fertilité chez l'homme.