CHIMERIC OPG POLYPEPTIDES

Chimeric polypeptides comprising fusions of an osteoprotegerin dimerization domain to a heterologous sequence are provided. Also provided are nucleic acids encoding the polypeptides, expression vectors and host cells for their production and pharmaceutical compositions comprising the polypeptides. L...

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Bibliographic Details
Main Authors BOYLE, WILLIAM, J, WOODEN, SCOTT
Format Patent
LanguageEnglish
French
Published 05.11.1998
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Chimeric polypeptides comprising fusions of an osteoprotegerin dimerization domain to a heterologous sequence are provided. Also provided are nucleic acids encoding the polypeptides, expression vectors and host cells for their production and pharmaceutical compositions comprising the polypeptides. La présente invention concerne des polypeptides chimères comprenant des fusions d'un domaine de dimérisation d'une ostéoprotégérine et d'une séquence hétérologue. L'invention se rapporte également à des acides nucléiques codant les polypeptides, à des vecteurs d'expression et à des cellules hôtes destinées à leur production, et à des compositions pharmaceutiques contenant lesdits polypeptides.
Bibliography:Application Number: WO1998US08631