SUBSTITUTED OXADIAZOLE CYSTEINE PROTEASE INHIBITORS

The present invention relates to cystein protease inhibitors of general formula (I), wherein Z is a cysteine protease binding moiety; X and Y are S, O or optionally substituted N; and R1 is optionally substituted alkyl or aryl. Cette invention a trait à des inhibiteurs de la cystéine protéase répond...

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Main Authors GYORKOS, ALBERT, C, CHERONIS, JOHN, C, GOODFELLOW, VAL, S, GERRITY, JAMES, IVAN, SPRUCE, LYLE, W, LEIMER, AXEL, H, YOUNG, JOHN, M
Format Patent
LanguageEnglish
French
Published 05.11.1998
Edition6
Subjects
CHEMISTRY
GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC
GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
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Summary:The present invention relates to cystein protease inhibitors of general formula (I), wherein Z is a cysteine protease binding moiety; X and Y are S, O or optionally substituted N; and R1 is optionally substituted alkyl or aryl. Cette invention a trait à des inhibiteurs de la cystéine protéase répondant à la formule générale (I) dans laquelle Z représente une fraction de fixation de cystéine protéase, X et Y représentent S, O ou N éventuellement substitué et R1 représente un alkyle ou un aryle éventuellement substitué.
Bibliography:Application Number: WO1998US08259