USE OF ANGIOTENSIN II ANTAGONISTS TO TREAT SYMPTOMATIC HEART FAILURE

Angiotensin II receptor antagonists are useful in reducing and preventing mortality and sudden cardiac death in symptomatic heart failure patients. Losartan potassium has been shown to reduce mortality and sudden cardiac death in this patient population. Additionally, losartan potassium has been sho...

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Main Authors SNAVELY, DUANE, B, RUCINSKA, EWA, J, BEERE, POLLY, A, PITT, BERTRAM, SEGAL, ROBERT, SHARMA, DIVAKAR, CHANG, PAUL, I
Format Patent
LanguageEnglish
French
Published 16.07.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Angiotensin II receptor antagonists are useful in reducing and preventing mortality and sudden cardiac death in symptomatic heart failure patients. Losartan potassium has been shown to reduce mortality and sudden cardiac death in this patient population. Additionally, losartan potassium has been shown to reduce the need for hospitalization of symptomatic heart failure patients. La présente invention concerne des antagonistes de récepteurs d'angiotensine II utilisés dans la réduction et la prévention de la mortalité et la mort cardiaque soudaine chez des patients présentant des insuffisances cardiaques symptomatiques. Le losartan potassique s'est avéré réduire la mortalité et la mort cardiaque soudaine dans cette population de patients. En outre, le losartan potassique s'est avéré réduire le besoin d'hospitalisation pour les patients présentant des insuffisances cardiaques symptomatiques.
Bibliography:Application Number: WO1998US00534