PYRAZOLES AS HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A2 INHIBITORS

A class of novel pyrazoles is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock. Nouvelle classe de pyrazoles et utilisation de ces composés pour inhiber la libération d'acides gras induite par...

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Bibliographic Details
Main Authors DOMAN, PETER, J, HITE, GARY, A, MIHELICH, EDWARD, D, SUAREZ, TULIO, WILLETTS, STUART, E
Format Patent
LanguageEnglish
French
Published 11.06.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A class of novel pyrazoles is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock. Nouvelle classe de pyrazoles et utilisation de ces composés pour inhiber la libération d'acides gras induite par sPLA2 dans le traitement de maladies telles que le choc septique.
Bibliography:Application Number: WO1997US21795