ENANTIOMERICALLY PURE 2-AMINOPURINE PHOSPHONATE NUCLEOTIDE ANALOGS AS ANTIVIRAL AGENTS
Cyclic and acyclic 2-aminopurine phosphonate nucleotide analogs useful to treat herpes viral infections are provided in enantiomerically pure form. Pharmaceutical compositions and methods for treating herpes viral infections are provided as well, as is a chiral synthesis for preparing the novel comp...
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| Main Authors | , , |
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| Format | Patent |
| Language | English French |
| Published |
06.11.1997
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| Edition | 6 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Cyclic and acyclic 2-aminopurine phosphonate nucleotide analogs useful to treat herpes viral infections are provided in enantiomerically pure form. Pharmaceutical compositions and methods for treating herpes viral infections are provided as well, as is a chiral synthesis for preparing the novel compounds in enantiomerically pure form.
Des analogues nucléotidiques cycliques et acycliques de 2-aminopurine phosphonate utilisés dans le traitement des infections à herpèsvirus sont produits sous une forme énantiomériquement pure. L'invention se rapporte également à des compositions pharmaceutiques et à des procédés de traitement des infections à herpèsvirus ainsi qu'à une synthèse chirale permettant la préparation desdits nouveaux composés sous une forme énantiomériquement pure. |
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| AbstractList | Cyclic and acyclic 2-aminopurine phosphonate nucleotide analogs useful to treat herpes viral infections are provided in enantiomerically pure form. Pharmaceutical compositions and methods for treating herpes viral infections are provided as well, as is a chiral synthesis for preparing the novel compounds in enantiomerically pure form.
Des analogues nucléotidiques cycliques et acycliques de 2-aminopurine phosphonate utilisés dans le traitement des infections à herpèsvirus sont produits sous une forme énantiomériquement pure. L'invention se rapporte également à des compositions pharmaceutiques et à des procédés de traitement des infections à herpèsvirus ainsi qu'à une synthèse chirale permettant la préparation desdits nouveaux composés sous une forme énantiomériquement pure. |
| Author | REIST, ELMER, J BRADFORD, WALLACE, W ZAVERI, NURULAIN, T |
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| DocumentTitleAlternate | ANALOGUES NUCLEOTIDIQUES DE 2-AMINOPURINE PHOSPHONATE ENANTIOMERIQUEMENT PURS UTILISES COMME AGENTS ANTIVIRAUX |
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| Notes | Application Number: WO1997US07100 |
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| Snippet | Cyclic and acyclic 2-aminopurine phosphonate nucleotide analogs useful to treat herpes viral infections are provided in enantiomerically pure form.... |
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| Title | ENANTIOMERICALLY PURE 2-AMINOPURINE PHOSPHONATE NUCLEOTIDE ANALOGS AS ANTIVIRAL AGENTS |
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