NOVEL ANTIBIOTIC, PROCESS FOR THE PREPARATION OF THE SAME, AND DRUG COMPOSITION CONTAINING THE SAME

An antifungal and antilipemic agent comprising substance MK6059 of the following general formula (I) which is prepared by culturing a MK6059 strain belonging to the genus Ellisiodothis in a conventional nutrient medium for microbes, and subjecting the resulting system to extraction with solvent, ion...

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Bibliographic Details
Main Authors SASAKI, TORU, KONNO, FUKIO, SATO, YOSHIKAZU, HARIMAYA, KENZO, CHIBA, NORIKO, KANDA, MINA, MIKAWA, TAKASHI
Format Patent
LanguageEnglish
French
Japanese
Published 16.10.1997
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
SPIRITS
STEROIDS
VINEGAR
WINE
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Summary:An antifungal and antilipemic agent comprising substance MK6059 of the following general formula (I) which is prepared by culturing a MK6059 strain belonging to the genus Ellisiodothis in a conventional nutrient medium for microbes, and subjecting the resulting system to extraction with solvent, ion exchange, silica gel chromatography, gel filtration chromatography or the like to isolate the objective substance. Cette invention concerne un agent antifongique et antilipémique qui comprend la substance MK6059 correspondant à la formule générale (I). Cette substance est préparée en cultivant un brin de MK6059 appartenant au genre Ellisiodothis dans un milieu nutritif traditionnel pour microbes. On soumet ensuite le système obtenu à une extraction par solvant, à un échange ionique, à une chromatographie sur gel de silice, à une chromatographie de filtration sur gel, ou analogue, ceci de manière à isoler la substance voulue.
Bibliography:Application Number: WO1997JP01221