METHOD OF PURIFYING FLUOROMETHYL 1,1,1,3,3,3-HEXAFLUOROISOPROPYL ETHER
A method of purifying fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether by distilling the crude ether in the presence of a compound selected from among hydroxides, hydrogenphosphates, phosphates, hydrogencarbonates, borates and sulfites of alkali metals, alkali metal acetates and phthalates, and bo...
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Main Authors | , , , |
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Format | Patent |
Language | English French Japanese |
Published |
12.10.1995
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | A method of purifying fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether by distilling the crude ether in the presence of a compound selected from among hydroxides, hydrogenphosphates, phosphates, hydrogencarbonates, borates and sulfites of alkali metals, alkali metal acetates and phthalates, and boric acid. According to this method, a highly pure fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether to be used as a medicine, especially as an inhalation anesthetic, can be produced by effectively inhibiting the decomposition of the ether in the distillation step.
Un procédé permet de purifier l'éther de fluorométhyle 1,1,1,3,3,3-hexafluoro-isopropyle en distillant cet éther brut en présence d'un composé choisi parmi les hydroxydes, hydrogénophosphates, phosphates, hydrogénocarbonates, borates et sulfites de métaux alcalins, les acétates et phtalates de métaux alcalins et l'acide borique. Par ce procédé, on peut produire un éther de fluorométhyle 1,1,1,3,3,3-hexafluoro-isopropyle très pur, qu'on peut utiliser comme substance à usage médical et en particulier comme anesthésique à inhaler, en inhibant efficacement la décomposition de cet éther pendant la phase de distillation. |
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Bibliography: | Application Number: WO1995JP00537 |